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Beyond strategy: The secret ingredient of innovation

On the path to success, organizations define strategies, plan each step, and invest in crucial resources such as the sale of services and products, project applications, the development of solid business plans, and the protection of intellectual property. However, there is an often-neglected element that is fundamental to the flourishing of innovation: serendipity. But what exactly is this mysterious force, and why is it so vital to advancing agriculture and so many other areas?

When chance opens doors: The power of unplanned discovery

Serendipity lies in the art of finding something valuable when looking for something else. It's the unintentional discoveries that arise from unexpected situations. Throughout history, some of the most transformative innovations have not been the result of a rigorous plan, but rather of a fortuitous encounter with the unknown. Although deliberate research and methodical experimentation are pillars of scientific and technological progress, openness to the unexpected proves to be a powerful catalyst. When researchers cultivate this openness, they often come across revelations that have the potential to revolutionize entire industries, transform technologies, and expand our understanding of the world around us.

A close look at the “error”: The genesis of an innovative biofungicide

Today, we unveil the surprising and inspiring story of Maria Miguel, a talented researcher from the InPP's New Biopesticides Department, whose insight transformed a fortuitous event into a discovery of inestimable value: a broad-spectrum biofungicide capable of combating Botrytis cinerea, the relentless fungus responsible for the devastating gray mold disease in tomato plants. This pathology represents one of the greatest phytosanitary challenges in tomato cultivation, especially when grown in greenhouses, causing significant losses to producers if not controlled in a timely manner.

From discard to discovery: An investigator's insight

The journey of this discovery began in a scenario familiar to any researcher: the observation of Petri dishes, used to grow cell or microorganism cultures. In Maria Miguel's Petri dishes, colonies of the fungus Botrytis cinerea were growing, intentionally introduced there for study. However, something else caught her attention: one of the plates was contaminated by mold, and curiously, a clear zone surrounded this intruder. Instead of discarding the plate and ignoring it as mere contamination, Maria Miguel decided to investigate the reason behind that clear area. Her curiosity revealed that the mold had a surprising ability to inhibit the growth of Botrytis cinerea in its vicinity.

“Sometimes we look at something and think it's a mistake. The truth is that within a failure, there can be something good,” shares the researcher. The emotion and enthusiasm of a researcher when realizing that what at first seemed like an obstacle, a negative result, can actually be an opportunity, is contagious. For Maria Miguel, this “error” transformed into a serendipitous discovery with enormous potential.

Maria Miguel, a researcher at the InPP's Department of New Biopesticides, transformed an unexpected event into a groundbreaking discovery: a broad-spectrum biofungicide to combat gray mold in tomato plants.

Beyond chance: The active ingredients of scientific discovery

As the story of this biofungicide demonstrates, the world of science is full of examples of discoveries that arose from the unexpected. One of the most famous cases is the discovery of penicillin by Alexander Fleming in 1928. While observing Petri dishes, Fleming noticed that a mold was producing a substance that eliminated Staphylococcus aureus bacteria around it. He identified the mold as Penicillium notatum and named his revolutionary antibiotic penicillin. Penicillin ended up becoming an extremely important drug for fighting infections.

However, chance is not the only protagonist of these important revelations. “Sometimes we have to follow our intuition and be able to prove that we are right or wrong,” explains Maria Miguel. In addition to intuition, a generous dose of curiosity, an open mind to accept unexpected results, a solid scientific knowledge, and the ability to see and advance to further investigations on surprising results play a crucial role in the alchemy of discovery.

The ecosystem of discovery: Fostering an environment conducive to innovation

There are other ingredients that contribute to the recipe for scientific success:

  • Creativity: The ability to generate new perspectives, concepts, questions, or solutions, and the willingness to explore existing ideas under a new light.
  • Flexibility: The courage to venture into unknown territories without fear of failure, thus increasing the odds of serendipitous encounters.

But no discovery flourishes in isolation. At InPP, the strong team spirit and culture of collaboration transcend departmental boundaries. Maria Miguel's discovery is a testament to this synergy, as she herself acknowledges: “My colleagues opened doors so that I could do my research.”

To foster innovation, organizations need to cultivate an environment that stimulates open discussions and connects people from diverse areas of knowledge and life experiences, without judgment; that encourages curiosity and receptiveness to new experiences; and that promotes a relentless pursuit of improving scientific knowledge, the fertile ground where serendipity can germinate.

Sowing the future: The impact of a discovery and the path of research

Although Maria Miguel is about to embark on a new journey, driven by a prestigious Marie Skłodowska-Curie doctoral fellowship - a program that supports the career of researchers and promotes excellence and innovation in research - her legacy at InPP is already flourishing. Her innovative discovery is opening new and promising doors for future research in the area of crop protection, demonstrating how, at times, it is in the unexpected that the potential to transform our world lies.

Beyond strategy: The secret ingredient of innovation

On the road to success, organizations define strategies, plan every step and invest in crucial resources such as selling services and products, applying for projects, drawing up solid business plans and protecting intellectual property. However, there is an element that is often overlooked, but which is fundamental to the flourishing of innovation: serendipity. But what exactly is this mysterious force and why is it so vital to the advancement of agriculture and so many other areas?

When chance opens doors: The power of unplanned discovery

Serendipity is the art of finding something valuable when you're looking for something else. It's the unintentional discoveries that arise from unexpected situations. Throughout history, some of the most transformative innovations have not been the result of a rigorous plan, but rather a chance encounter with the unknown. While deliberate research and methodical experimentation are pillars of scientific and technological progress, openness to the unexpected proves to be a powerful catalyst. When researchers cultivate this openness, they often stumble upon revelations that have the potential to revolutionize entire industries, transform technologies and expand our understanding of the world around us.

A close look at “error”: The genesis of an innovative biofungicide

Today, we unveil the surprising and inspiring story of Maria Miguel, a talented researcher from InPP's New Biopesticides Department, whose acumen turned a chance event into a priceless discovery: a broad-spectrum biofungicide capable of combating the Botrytis cinerea, the relentless fungus responsible for the devastating gray rot disease in tomato plants. This pathology represents one of the biggest phytosanitary challenges in tomato cultivation, especially when grown in greenhouses, causing significant losses to producers if it is not controlled in good time.

From discard to discovery: The insight of a researcher

The journey of this discovery began in a setting familiar to any researcher: the observation of Petri dishes, used to grow cultures of cells or microorganisms. On Maria Miguel's plates, colonies of the fungus Botrytis cinerea were growing, intentionally introduced there for study. However, something else caught her eye: one of the plates was contaminated by mold, and curiously, a clear area surrounded this intruder. Instead of discarding the plate and dismissing it as mere contamination, Maria Miguel decided to investigate the reason behind the clear area. Her curiosity revealed that the mold had a surprising ability to prevent the growth of Botrytis cinerea in its vicinity.

“Sometimes we look at something and think it's a mistake. The truth is that in a failure there can be something good,” the researcher shares. The excitement and enthusiasm of a researcher realizing that what at first glance seemed like an obstacle, a negative result, could actually be an opportunity, is contagious. For Maria Miguel, this “mistake” turned into a serendipitous discovery with enormous potential.

Maria Miguel, a researcher at InPP's New Biopesticides Department, who turned an unexpected event into a discovery that changed the course of her work: a broad-spectrum biofungicide to combat gray rot in tomato plants.

Beyond chance: The active ingredients of scientific discovery

As the history of this biofungicide shows, the world of science is full of examples of discoveries that came out of the blue. One of the most famous cases is Alexander Fleming's discovery of penicillin in 1928. While observing Petri dishes, Fleming noticed that a mold was producing a substance that eliminated bacteria Staphylococcus aureus around him. He identified the mold as Penicillium notatum and named his revolutionary antibiotic penicillin. Penicillin ended up becoming an extremely important medicine for fighting infections.

However, chance is not the only protagonist of these important revelations. “Sometimes we have to follow our intuition and be able to prove ourselves right or wrong,” explains Maria Miguel. In addition to intuition, a generous dose of curiosity, an open mind to accept unexpected results, solid scientific knowledge and the ability to see and move on to further research into surprising results play a crucial role in the alchemy of discovery.

The discovery ecosystem: Fostering an environment conducive to innovation

There are other ingredients that contribute to the recipe for scientific success:

  • Creativity: The ability to generate new perspectives, concepts, questions or solutions, and the willingness to explore existing ideas in a new light.
  • Flexibility: The courage to venture into unknown territory without the fear of failure, thus increasing the chances of serendipitous encounters.

But no discovery flourishes in isolation. At InPP, the strong team spirit and culture of collaboration transcend departmental boundaries. The case of Maria Miguel's discovery is testimony to this synergy, as she herself acknowledges: “My colleagues opened doors so that I could do my research”.

To foster innovation, organizations need to cultivate an environment that encourages open discussions and connects people from different areas of knowledge and life experiences, without judgment; that encourages curiosity and receptiveness to new experiences; and that promotes an incessant quest to improve scientific knowledge, the fertile ground where serendipity can germinate.

Sowing the future: The impact of a discovery and the path of research

Although Maria Miguel is about to embark on a new journey, boosted by a prestigious Marie Skłodowska-Curie PhD scholarship - a program that supports the careers of researchers and promotes excellence and innovation in research - her legacy at InPP is already flourishing. Her groundbreaking discovery is opening promising new doors for future research in the field of crop protection, demonstrating how sometimes it is in the unexpected that the potential to transform our world lies.

In the March issue of Fruits, vegetables and flowers you will find the opinion article entitled “The role of InnovPlantProtect in Organic Farming: Paths to sustainable and efficient solutions”, in which the executive director of InnovPlantProtect (InPP), António Saraiva, reveals how our CoLAB is contributing to the success of organic farming.

“By boosting research, collaboration and knowledge sharing, InPP is helping to solve the central challenges of this practice [organic farming], allowing it to expand and enhancing the supply of agricultural products to consumers. The solutions developed by InPP make organic farming a more viable option for producers,” says the executive director.

Read the full article and find out how we are shaping the future of agriculture.

We thank Frutas, legumes e flores magazine for its recognition and reiterate our commitment to the agriculture of the future.

EVENTS

The Department of Formulations and Process Development for the Application of Biopesticides is dedicated to the design and production of encapsulation and transport systems, suitable for protecting our biological agents from the degradation that occurs during prolonged storage and during application. These protective and carrier systems, which are nanometric and micrometric in size, will be incorporated into solid and liquid formulations in a format that adapts to the specific agricultural application for which they have been designed.

Formulations can be solid or liquid.

After understanding the specific needs of each bioagent, we adjust the characteristics of the respective transport systems accordingly and also focus on developing viable manufacturing processes, potentially scalable to industrial volumes.

Solid nanoparticles, lipid nanoemulsions and polymeric microcapsules will be developed, obtained using precise and sophisticated processes already adopted by the industry. Innovation will be sought through the use of sustainable ingredients and combinations with previous systems, for easier adoption by the biocontrol market.

Image by Hans Reniers | Unsplash

“The current legislation on GMOs [genetically modified organisms], adopted in 2001, is not suitable for the new genomic techniques (NTG),” says the long-awaited study published by the European Commission (EC) at the request of the Council of the European Union (EU). O document led the EC to announce which will “initiate a broad and open consultation process to discuss the design of a new legal framework for these biotechnologies”.

“The study shows that NTG, which are techniques for altering the genome of an organism, have the potential to contribute to a more sustainable food system within the framework of the objectives of the European Green Deal and Farm to Fork Strategy“, says the EC statement. “With consumer and environmental safety as the guiding principle, the time has come to establish an open dialogue with citizens, Member States and the European Parliament in order to decide together on the way forward for the use of these biotechnologies in the EU,” stresses Stella Kyriakides, Commissioner for Health and Food Safety.

“NTGs have the potential to contribute to a more sustainable food system.”

The report identifies limitations to the legislation's ability to keep up with scientific developments, causing implementation challenges and illegal uncertainties, which need to be resolved. It recognizes that it may not be justifiable to apply different levels of regulatory oversight to products with similar degrees of risk, as in the case of conventionally improved plants and those obtained from certain NTGs.

“Future regulatory actions will need to address the knowledge gaps and limitations identified in this study.” In addition, “a greater effort should be made to inform and involve the public regarding NGTs, and to assess their opinions,” admits the EC.

Entitled ‘Study on the status of new genomic techniques under Union law and in light of the Court of Justice ruling in Case C-528/16’, the study examines the current state of NTG, “taking into account the ‘state of the art’ of knowledge and the views of EU countries and stakeholders”. The Council of the EU requested this state of play on NTG under European law (Directive 2001/18/ECRegulation (EC) 1829/2003Directive 2009/41/EC e Regulation (EC) 1830/2003), in the light of the judgment of the Court of Justice in Case C-528/16.

Image by Congerdesign | Pixabay

“The current GMO legislation, adopted in 2001, is not fit for purpose for New Genomic Techniques (NGTs)”, says the awaited study published by the European Commission (EC), at the request of the EU Council. The document prompted the EC to announce the start of a “wide and open consultation process to discuss the design of a new legal framework for these biotechnologies”.

“The study shows that NGTs, which are techniques to alter the genome of an organism, have the potential to contribute to a more sustainable food system as part of the objectives of the European Green Deal and the Farm to Fork Strategy”, states the EC in the related press release. “With the safety of consumers and the environment as the guiding principle, now is the moment to have an open dialogue with citizens, Member States and the European Parliament to jointly decide the way forward for the use of these biotechnologies in the EU”, emphasizes Stella Kyriakides, Commissioner for Health and Food Safety.

The study identifies limitations to the capacity of legislation to keep pace with scientific developments, causing implementation challenges and legal uncertainties, which need to be addressed. It recognizes it may not be justified to apply different levels of regulatory oversight to similar products with similar levels of risk, as is the case for plants conventionally bred and obtained from certain NGTs.

“Future policy action would need to address the knowledge gaps and limitations identified in this study”. Furthermore, “importantly, more effort should be made to inform and engage with the public on NGTs and assess their views”, admits the EC.

Entitled ‘Study on the status of new genomic techniques under Union law and in light of the Court of Justice ruling in Case C-528/16’, the report examines the status of NGTs “taking into account the state of the art knowledge and the views of the EU countries and stakeholders”. The Council of the European Union asked for this study, regarding the status of new genomic techniques under Union Law (Directive 2001/18/ECRegulation (EC) 1829/2003Directive 2009/41/EC and Regulation (EC) 1830/2003), in light of the Court of Justice's judgment in Case C-528/16.

Image by Congerdesign, from Pixabay