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Beyond strategy: The secret ingredient of innovation

On the path to success, organizations define strategies, plan each step, and invest in crucial resources such as the sale of services and products, project applications, the development of solid business plans, and the protection of intellectual property. However, there is an often-neglected element that is fundamental to the flourishing of innovation: serendipity. But what exactly is this mysterious force, and why is it so vital to advancing agriculture and so many other areas?

When chance opens doors: The power of unplanned discovery

Serendipity lies in the art of finding something valuable when looking for something else. It's the unintentional discoveries that arise from unexpected situations. Throughout history, some of the most transformative innovations have not been the result of a rigorous plan, but rather of a fortuitous encounter with the unknown. Although deliberate research and methodical experimentation are pillars of scientific and technological progress, openness to the unexpected proves to be a powerful catalyst. When researchers cultivate this openness, they often come across revelations that have the potential to revolutionize entire industries, transform technologies, and expand our understanding of the world around us.

A close look at the “error”: The genesis of an innovative biofungicide

Today, we unveil the surprising and inspiring story of Maria Miguel, a talented researcher from the InPP's New Biopesticides Department, whose insight transformed a fortuitous event into a discovery of inestimable value: a broad-spectrum biofungicide capable of combating Botrytis cinerea, the relentless fungus responsible for the devastating gray mold disease in tomato plants. This pathology represents one of the greatest phytosanitary challenges in tomato cultivation, especially when grown in greenhouses, causing significant losses to producers if not controlled in a timely manner.

From discard to discovery: An investigator's insight

The journey of this discovery began in a scenario familiar to any researcher: the observation of Petri dishes, used to grow cell or microorganism cultures. In Maria Miguel's Petri dishes, colonies of the fungus Botrytis cinerea were growing, intentionally introduced there for study. However, something else caught her attention: one of the plates was contaminated by mold, and curiously, a clear zone surrounded this intruder. Instead of discarding the plate and ignoring it as mere contamination, Maria Miguel decided to investigate the reason behind that clear area. Her curiosity revealed that the mold had a surprising ability to inhibit the growth of Botrytis cinerea in its vicinity.

“Sometimes we look at something and think it's a mistake. The truth is that within a failure, there can be something good,” shares the researcher. The emotion and enthusiasm of a researcher when realizing that what at first seemed like an obstacle, a negative result, can actually be an opportunity, is contagious. For Maria Miguel, this “error” transformed into a serendipitous discovery with enormous potential.

Maria Miguel, a researcher at the InPP's Department of New Biopesticides, transformed an unexpected event into a groundbreaking discovery: a broad-spectrum biofungicide to combat gray mold in tomato plants.

Beyond chance: The active ingredients of scientific discovery

As the story of this biofungicide demonstrates, the world of science is full of examples of discoveries that arose from the unexpected. One of the most famous cases is the discovery of penicillin by Alexander Fleming in 1928. While observing Petri dishes, Fleming noticed that a mold was producing a substance that eliminated Staphylococcus aureus bacteria around it. He identified the mold as Penicillium notatum and named his revolutionary antibiotic penicillin. Penicillin ended up becoming an extremely important drug for fighting infections.

However, chance is not the only protagonist of these important revelations. “Sometimes we have to follow our intuition and be able to prove that we are right or wrong,” explains Maria Miguel. In addition to intuition, a generous dose of curiosity, an open mind to accept unexpected results, a solid scientific knowledge, and the ability to see and advance to further investigations on surprising results play a crucial role in the alchemy of discovery.

The ecosystem of discovery: Fostering an environment conducive to innovation

There are other ingredients that contribute to the recipe for scientific success:

  • Creativity: The ability to generate new perspectives, concepts, questions, or solutions, and the willingness to explore existing ideas under a new light.
  • Flexibility: The courage to venture into unknown territories without fear of failure, thus increasing the odds of serendipitous encounters.

But no discovery flourishes in isolation. At InPP, the strong team spirit and culture of collaboration transcend departmental boundaries. Maria Miguel's discovery is a testament to this synergy, as she herself acknowledges: “My colleagues opened doors so that I could do my research.”

To foster innovation, organizations need to cultivate an environment that stimulates open discussions and connects people from diverse areas of knowledge and life experiences, without judgment; that encourages curiosity and receptiveness to new experiences; and that promotes a relentless pursuit of improving scientific knowledge, the fertile ground where serendipity can germinate.

Sowing the future: The impact of a discovery and the path of research

Although Maria Miguel is about to embark on a new journey, driven by a prestigious Marie Skłodowska-Curie doctoral fellowship - a program that supports the career of researchers and promotes excellence and innovation in research - her legacy at InPP is already flourishing. Her innovative discovery is opening new and promising doors for future research in the area of crop protection, demonstrating how, at times, it is in the unexpected that the potential to transform our world lies.

Beyond strategy: The secret ingredient of innovation

On the road to success, organizations define strategies, plan every step and invest in crucial resources such as selling services and products, applying for projects, drawing up solid business plans and protecting intellectual property. However, there is an element that is often overlooked, but which is fundamental to the flourishing of innovation: serendipity. But what exactly is this mysterious force and why is it so vital to the advancement of agriculture and so many other areas?

When chance opens doors: The power of unplanned discovery

Serendipity is the art of finding something valuable when you're looking for something else. It's the unintentional discoveries that arise from unexpected situations. Throughout history, some of the most transformative innovations have not been the result of a rigorous plan, but rather a chance encounter with the unknown. While deliberate research and methodical experimentation are pillars of scientific and technological progress, openness to the unexpected proves to be a powerful catalyst. When researchers cultivate this openness, they often stumble upon revelations that have the potential to revolutionize entire industries, transform technologies and expand our understanding of the world around us.

A close look at “error”: The genesis of an innovative biofungicide

Today, we unveil the surprising and inspiring story of Maria Miguel, a talented researcher from InPP's New Biopesticides Department, whose acumen turned a chance event into a priceless discovery: a broad-spectrum biofungicide capable of combating the Botrytis cinerea, the relentless fungus responsible for the devastating gray rot disease in tomato plants. This pathology represents one of the biggest phytosanitary challenges in tomato cultivation, especially when grown in greenhouses, causing significant losses to producers if it is not controlled in good time.

From discard to discovery: The insight of a researcher

The journey of this discovery began in a setting familiar to any researcher: the observation of Petri dishes, used to grow cultures of cells or microorganisms. On Maria Miguel's plates, colonies of the fungus Botrytis cinerea were growing, intentionally introduced there for study. However, something else caught her eye: one of the plates was contaminated by mold, and curiously, a clear area surrounded this intruder. Instead of discarding the plate and dismissing it as mere contamination, Maria Miguel decided to investigate the reason behind the clear area. Her curiosity revealed that the mold had a surprising ability to prevent the growth of Botrytis cinerea in its vicinity.

“Sometimes we look at something and think it's a mistake. The truth is that in a failure there can be something good,” the researcher shares. The excitement and enthusiasm of a researcher realizing that what at first glance seemed like an obstacle, a negative result, could actually be an opportunity, is contagious. For Maria Miguel, this “mistake” turned into a serendipitous discovery with enormous potential.

Maria Miguel, a researcher at InPP's New Biopesticides Department, who turned an unexpected event into a discovery that changed the course of her work: a broad-spectrum biofungicide to combat gray rot in tomato plants.

Beyond chance: The active ingredients of scientific discovery

As the history of this biofungicide shows, the world of science is full of examples of discoveries that came out of the blue. One of the most famous cases is Alexander Fleming's discovery of penicillin in 1928. While observing Petri dishes, Fleming noticed that a mold was producing a substance that eliminated bacteria Staphylococcus aureus around him. He identified the mold as Penicillium notatum and named his revolutionary antibiotic penicillin. Penicillin ended up becoming an extremely important medicine for fighting infections.

However, chance is not the only protagonist of these important revelations. “Sometimes we have to follow our intuition and be able to prove ourselves right or wrong,” explains Maria Miguel. In addition to intuition, a generous dose of curiosity, an open mind to accept unexpected results, solid scientific knowledge and the ability to see and move on to further research into surprising results play a crucial role in the alchemy of discovery.

The discovery ecosystem: Fostering an environment conducive to innovation

There are other ingredients that contribute to the recipe for scientific success:

  • Creativity: The ability to generate new perspectives, concepts, questions or solutions, and the willingness to explore existing ideas in a new light.
  • Flexibility: The courage to venture into unknown territory without the fear of failure, thus increasing the chances of serendipitous encounters.

But no discovery flourishes in isolation. At InPP, the strong team spirit and culture of collaboration transcend departmental boundaries. The case of Maria Miguel's discovery is testimony to this synergy, as she herself acknowledges: “My colleagues opened doors so that I could do my research”.

To foster innovation, organizations need to cultivate an environment that encourages open discussions and connects people from different areas of knowledge and life experiences, without judgment; that encourages curiosity and receptiveness to new experiences; and that promotes an incessant quest to improve scientific knowledge, the fertile ground where serendipity can germinate.

Sowing the future: The impact of a discovery and the path of research

Although Maria Miguel is about to embark on a new journey, boosted by a prestigious Marie Skłodowska-Curie PhD scholarship - a program that supports the careers of researchers and promotes excellence and innovation in research - her legacy at InPP is already flourishing. Her groundbreaking discovery is opening promising new doors for future research in the field of crop protection, demonstrating how sometimes it is in the unexpected that the potential to transform our world lies.

In the March issue of Fruits, vegetables and flowers you will find the opinion article entitled “The role of InnovPlantProtect in Organic Farming: Paths to sustainable and efficient solutions”, in which the executive director of InnovPlantProtect (InPP), António Saraiva, reveals how our CoLAB is contributing to the success of organic farming.

“By boosting research, collaboration and knowledge sharing, InPP is helping to solve the central challenges of this practice [organic farming], allowing it to expand and enhancing the supply of agricultural products to consumers. The solutions developed by InPP make organic farming a more viable option for producers,” says the executive director.

Read the full article and find out how we are shaping the future of agriculture.

We thank Frutas, legumes e flores magazine for its recognition and reiterate our commitment to the agriculture of the future.

EVENTS

On March 18th, InnovPlantProtect (InPP) took part in the Ucanorte XXI Field Day, organized by our associate Fertiprado.

The morning kicked off with an auditorium session featuring InPP. António Saraiva, executive director of CoLAB, introduced InPP and the different innovative solutions and technologies that are being developed to protect crops. Ricardo Ramiro, director of the Data Management and Risk Analysis department, was another speaker who presented the services that can be of use to corn silage producers.

Samira Andrade, a researcher at Fertiprado, shared the promising results of her collaboration with the InPP team on seed coating.

Many thanks to Fertiprado for the invitation and the opportunity to strengthen our partnership!

Image credits: Fertiprado

Photos from left to right: António Saraiva, executive director of InPP; Ricardo Ramiro, director of the Data Management and Risk Analysis department and Samira Andrade, Fertiprado researcher collaborating with CoLAB.

InPP is the leader of a project that aims to develop sustainable and effective biopesticides to control two of the most important diseases of the olive grove, gafa and tuberculosis. This biopesticide, obtained from the plant biomass left over from the production of cannabis for medicinal purposes, will innovate and boost sustainability in this booming industry in Portugal. With an investment of 150,000 euros from the “la Caixa” Foundation, ValorCannBio promises to revolutionize the sector, positioning it as an important player in the circular economy and in reducing waste.

You have to travel to the heart of the Mediterranean, one of the regions most vulnerable to climate change, to get to the olive grove, an ancient crop and economic engine, and understand the uphill battle it faces. Gafa and tuberculosis, two of the most important olive diseases, threaten the production of olive oil, one of Portugal's most valuable export products, especially in the Alentejo, where 75% of national production is concentrated.

Gafa, caused by the fungus Colletotrichum sp., can decimate up to 80% of production, representing losses of more than 50 million euros and threatening traditional Portuguese varieties such as Galega. Tuberculosis, caused by the bacterium Pseudomonas savastanoi pv. savastanoi (Pss), compromises the quality of olive oil, and current copper-based control methods are ineffective and harmful to the environment.

Left photo: Olive grove, agricultural crop in focus of the ValorCannBio project; Center photo: Olive infected with the fungus Colletotrichum, The bacterium, which causes gafa, one of the most important diseases of the olive grove; Photo on the right: Olive tree infected with the bacterium Pseudomonas savastanoi, which causes tuberculosis, one of the most important diseases of the olive grove.

Cannabis: A New Hope for the Olive Grove

In a promising turnaround, the production of medical cannabis (with the scientific name Cannabis sativa) flourishes in Portugal, including in the Alentejo, with the country on its way to becoming one of the world's largest producers. However, the flower, rich in valuable compounds such as THC and CBD, is the only part of the plant that is used, while the remaining biomass legally has to be incinerated, a process with high economic and environmental costs.

What if this biomass, with its more than 500 chemical compounds, some of which have proven antibacterial and antifungal properties that are already known and others that have yet to be discovered, could be transformed into a solution to the challenges facing the olive grove? This is where the ValorCannBio: Valorization of medicinal cannabis by-products as a biopesticide for olive groves, a beacon of innovation and sustainability.

ValorCannBio: Science and Sustainability in Action

Led by InPP, in partnership with NOVA FCT's Associated Laboratory for Green Chemistry (LAQV requimte) and the companies GreenBePharma (GBP) and AGR Global, ValorCannBio is transforming surplus biomass from medical cannabis into effective and sustainable biopesticides against Gafa and Tuberculosis.

This is the first time that InPP has joined projects related to innovation and sustainability in the cannabis production industry and it wants to play a decisive role in the value chain. “Our team of researchers is developing sustainable biofungicides and biobactericides, using new extraction methods with environmentally friendly solvents. We are creating solutions that increase the efficiency and sustainability of this industry,” says Tatiana Gil, an InPP researcher involved in the project.

But the team of researchers isn't stopping there. “We are still unraveling the secrets of endophytic cannabis bacteria, microorganisms that live in symbiosis with the plant, as biological control agents,” he adds.

And how do you turn a cannabis leaf into a shield for the olive grove? Tatiana Gil explains the process step by step: “First, we test the effectiveness of the extracts in the laboratory, like detectives looking for clues. Then we formulate the biopesticide and assess its impact in a greenhouse, in a controlled environment. Finally, we take the solution to the field for the final test.”.

Tatiana Gil, InnovPlantProtect researcher, analyzes samples of cannabis leaf extracts as part of the ValorCannBio project.

An Impact that extends across the Territory

Cristina Azevedo, InPP researcher and project leader, anticipates the impact of ValorCannBio: “All of these impacts will be felt in the municipality of Elvas, where the project will take place, but it is expected that they will extend to the entire olive-growing region from Trás-os-Montes to the Algarve, where production losses due to gafa and tuberculosis are increasing, and eventually to Mediterranean countries where these diseases are equally prevalent.”.

ValorCannBio not only aims to offer a sustainable alternative to chemical pesticides, but also opens up a new way of valorizing the remaining biomass of the cannabis plant that is not used for medicinal purposes, transforming it from a waste product into a valuable resource.

“We want to create a parallel and complementary industry to the production of medicinal cannabis, involving the production of biopesticides,” reveals Cristina Azevedo, “which will pave the way for other innovations,” she adds.

A Sustainable Future for the Olive Grove

The ValorCannBio project is an example of how innovation and sustainability can go hand in hand, offering solutions to the challenges of modern agriculture. By harnessing the potential of medicinal cannabis, ValorCannBio is helping to build a greener, more prosperous future for olive groves and the planet.

With the support of the “la Caixa” Foundation, in partnership with Banco BPI and the Foundation for Science and Technology (FCT), ValorCannBio, which began in October 2024, promises to be a success story until November 2027.

By the end of spring, the National Vector Insect Monitoring System project team will be working on the Xylella fastidiosa (SNM_XylellaVt), funded by the PRR, challenges citizens to keep an eye on plant foams: by detecting foams on plants, recording the data in the app and filling in the online form, it helps them to create an up-to-date map of the temporal and spatial distribution of the appearance of the juvenile stage of 4 species of leafhoppers in Portugal, which, once adult, are responsible for carrying the quarantine bacterium Xylella fastidiosa from one plant to another.

The presence of the bacteria has already been detected in Portugal Xylella fastidiosa in four species of leafhoppers in mainland Portugal, but little is known about the current temporal and spatial distribution of these insects in our country. With this in mind, the project team SNM_XylellaVt, challenges citizens to be on the lookout for foams, located mainly on the stems of plants, in their daily lives, on vacation in Portugal, or when walking in natural spaces, olive groves, vineyards, pastures, orchards or in the montado. Foams are signs of the presence of these insect species that are vectors for the transmission of the bacteria Xylella fastidiosa.

Left and center photos: Examples of foams found in plants; Right photo: foam leafhopper, an insect that transmits the bacteria. Xylella fastidiosa

“With the help of all citizens, we will be able to understand the population dynamics of insect vectors and their relationship with plants, which could help us plan measures to combat Xylella fastidiosa, preventing the spread of this bacterium. This is very relevant given that we don't have a direct curative treatment for this bacterium, which makes its control extremely difficult,” explains Ilaria Marengo, a partner in the SNM_XylellaVt project and researcher at InPP. “Destroying infected plants and controlling insect vectors are currently the main measures to prevent the spread of the bacterium,” she adds.

Everyone can contribute to the “Help us save your plants!” campaign that is currently underway: all you have to do is, when you spot the leafhopper foams, take photos of the foams, located on the stems of the plants, and of the plant where you found them, record the data in the ODK Collect 2024 application available for your cell phone (see image below), record the date and geographical location - if possible with GPS coordinates - or alternatively, submit this data using a online form on the project platform. Once you have submitted your data, you will be able to view it on the available map aqui.

Steps on how to install and use the ODK Collect 2024 application on your cell phone or tablet. To install, go to the guide on the DGAV website here.

The “Help us save your plants!” campaign is being developed as part of the SNM_XylellaVt project, which is currently underway. SNM_XylellaVt, led by the Centro Regional Coordination and Development Commission (CCDR CENTRO), and in which InPP is a partner, aims to contain the disease to the areas identified so far and to stop it spreading to the rest of Portugal. To this end, it is creating a network for monitoring the X. fastidiosa and its vector insect(s), in particular the foam leafhoppers, with the scientific name Philaenus spumarius, Philaenus tesselatus, Neophilaenus lineatus e Cicadella viridis, This will enable the development of new tools, such as risk forecasting models that will allow the National Agricultural Warning Service (SNAA) to warn in real time about the economic attack levels (NEA) for these insects, and prevent the spread of infection to crops that are relevant to national agriculture.

In 2019, the bacterium Xylella fastidiosa was first detected in Portugal, in the metropolitan area of Porto, and has since been detected in other areas of mainland Portugal. This bacterium attacks a wide range of plants, posing a risk to agricultural and forestry crops of significant economic importance.

For more information on the bacteria Xylella fastidiosa access the website of the Directorate-General for Food and Veterinary (DGAV) here.