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Elvas collaborative laboratory distinguished by Rural Life as “the most significant investment in the last year in the agricultural and agro-industrial sector”.

“Investment that makes a mark” 2021 is the name of the prize awarded today to InnovPlantProtect by Rural Life. The award, conferred by the editorial board of the professional agribusiness magazine, recognizes the most significant investment in the last year in the agricultural and agro-industrial sector at a national level.

The choice of the collaborative laboratory (CoLab), based in Elvas, “aims to reinforce the importance of investing in research and innovation in a key area for the future of agriculture: the search for biologically-based solutions for crop protection, in a challenging context, in which it is necessary to ensure the production of food in an increasingly sustainable way,” explains Isabel Martins, director of the company. Rural Life and publications coordinator at IFE.

This award “honors the initiative of the 12 founding partners to create an innovative institution to develop biological and digital solutions for crop protection,” says Pedro Fevereiro, the CoLab's executive director, adding: “It's an incentive for InnovPlantProtect, which set up in a low-density region and managed to attract 38 highly qualified human resources to set up a modern innovation unit. It also rewards the vision of the municipality of Elvas, which embraced this challenge from the outset.”

The “Investment that Makes a Mark” 2021 award was presented during the 8th edition of the AgroIn - Annual Agribusiness Congress, organized by Rural Life/ IFE, held in the auditorium of the Faculty of Dental Medicine of the University of Lisbon.

The InPP team, like scientists around the world, concludes that new techniques can mitigate the challenges posed by climate change and the continuing increase in the world's population.

We know that in order to feed the world's population in 2050, we will have to increase food production by 70% [1]. And we also know that agriculture is under intense pressure to meet the sustainability goals of the European Green Deal and Farm to Fork Strategy, This is under pressure from climate change and the increase in pests and diseases attacking crops.

A team from InnovPlantProtect (InPP) reviewed hundreds of scientific articles published in recent years and concluded that “genome editing is an important tool for improving food security in a sustainable way and mitigating the challenges posed by global climate change and the expansion of the world's population”. The review article [2], entitled Genome editing for resistance against plant pests and pathogens, has just been published in Transgenic Research.

“The development of new tools to improve plant protection is critical in the context of current agricultural, environmental and ecological challenges,” say the researchers, adding that “various efforts in the area of genome editing have resulted in plants with potentially beneficial characteristics that can be quickly and easily applied in the field.”.

The team analyzed the latest advances in genome editing with a view to improving plant protection, focusing on editing the genomes of crops, pests and pathogens based on the CRISPR-Cas technique (Nobel Prize in Chemistry in 2020). The researchers did not forget other technologies, such as host-induced gene silencing (HIGS) and the use of biocontrol agents, discussing how CRISPR-Cas can be used to accelerate the development of ecological strategies that promote sustainable agriculture in the future.

[HIGS consists of the plant producing small molecules of RNA (ribonucleic acid), which lead to the silencing of the pathogen's genes; silencing a gene means “canceling” its expression].

As genome editing does not require crossbreeding, the authors of the article point out, it avoids the introduction of unwanted characteristics through genetic linkage (a situation in which a gene with a positive characteristic is physically linked to a gene that confers negative characteristics) in improved varieties, speeding up the entire breeding process.

In addition, genome editing technologies can directly target the susceptibility genes or virulence factors of pests and pathogens, either by directly editing the genome of the pest in question, or by adding genome editing mechanisms to the plant genome, or to microorganisms that act as biocontrol agents.

Several studies have shown that the targeted inactivation of susceptibility genes through genome editing is a solid strategy for crop protection, capable of producing non-transgenic plants. The technique has been shown to be particularly effective in editing susceptibility genes to pathogenic bacteria and fungi.

“The potential impact of genome editing, and CRISPR technology in particular, on plant synthetic biology to improve resistance to pests and diseases is enormous and will have a direct effect on agricultural sustainability on a scale never seen before,” the team concludes.

Original article:

Rato, C., Carvalho, M.F., Azevedo, C. & Oblessuc, Paula. Genome editing for resistance against plant pests and pathogens. Transgenic Research (2021). https://doi.org/10.1007/s11248-021-00262-x

[1] How to Feed the World in 2050, FAO expert paper

[2] In a review article, researchers critically summarize what has already been studied and published by other scientists.