Biotechnology: agricultural revolution “just around the corner”

Nature Plants highlights the advantages of new genome editing techniques but warns of three crucial aspects that still need to be addressed.

“The rapid development of plant biotechnologies is profoundly shaping crop improvement and catalyzing the next revolution in agriculture,” writes an editorial recently published by Nature Plants, entitled Next-generation crop engineering (Next-generation crop engineering).

Crop improvement no longer has to depend on naturally occurring mutations and artificially generated variations can be the raw material for further improvement, the text argues. “A much broader spectrum of phenotypic space is ready for exploration, allowing the development of ideal phenotypes adapted to the heterogeneous environments of Earth, or even Space,” argue the authors of the paper. article, He concluded that “a new agricultural revolution driven by biotechnology could be just around the corner”.

The editorial refers to the promise and advantages of the new genome editing techniques, particularly compared to classical breeding, but not only. And it warns of three crucial factors that are still missing in order to achieve high levels of variation through gene editing: 1) a better understanding of the key regulators for genes that are important from an evolutionary or developmental point of view; 2) being able to dissect networks of genes that control phenotypes of interest and regulatory networks in cis that affect gene expression; 3) to establish stable and efficient transformation and regeneration procedures for most species.

Unless genetic editing in planta is developed quickly, breeding based on gene editing will be unable to benefit recalcitrant species. It is also recalled that there are alternative strategies for engineering new generation crops, such as the transfection of viral RNA in sprays, which allows for the temporary adjustment of agronomic characteristics without modifying the genetic material.