Comparing genomes to understand the “tricks” of microbes

Sometimes, if you're inside a building, it's hard to tell whether or not it's raining outside. However, you will easily conclude that it is raining if you see people with open umbrellas. The umbrella is an accessory that helps human beings deal with their environment.

Bacteria can also use “accessories” to better cope with their environments. These accessories, however, have much more profound effects on the lives of microbes, as they take the form of genes that can be integrated into their own genomes. These “accessory” genes are obtained from other microbes or from the environment, and can play various roles, from allowing bacteria to resist antibiotics to enabling symbiotic associations with plants.

At InPP, the Data Management and Risk Analysis Department is comparing bacterial genomes to identify those that have “accessory” genes that can help plants defend themselves better against pathogens. On the other hand, these analyses also allow us to rule out bacterial strains that could have adverse effects. This information will be crucial for identifying microbes and microbial characteristics that are important for plant protection.